GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 InChi: InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20

InChi: InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20

BAY 68-4986

InChiKey: RQZAXGRLVPAYTJ-GQFGMJRRSA-N

Chemical Name: 1-(2-{[3-(2-phenylethynyl)pyrido[2

TL13-110 also prompts the degradation of additional kinases including Aurora A

GNE-477 - CAS# 1032754-81-6 Catalog No.:M10487-2 InChi: InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20GNE 477 is a dual inhibitor of PI3K (IC50 = 4 nM for PI3K) and mTOR (apparent Ki = 21 nM). Product information CAS Number: 1032754 81 6 Molecular Weight: 504. 63 Formula: C21H28N8O3S2 Synonym: GNE477 GNE 477 Chemical Name: 5 {6 [(4 methanesulfonylpiperazin 1 yl)methyl] 7 methyl 4 (morpholin 4 yl)thieno[3,2 d]pyrimidin 2 yl}pyrimidin 2 amine Smiles: CC1C2=NC(=NC(=C2SC=1CN1CCN(CC1)S(C)(=O)=O)N1CCOCC1)C1=CN=C(N)N=C1 InChiKey: AKKCGLXULFRAET UHFFFAOYSA N