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PF-03084014 binds to GS
Tamibarotene
TM5275 prolongs secreted tissue plasminogen activator retention and enhances fibrinolysis on vascular endothelial cells
ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4
Smiles: CC1=CC=C(C=C1Br)C(=O)N/N=C(\C)/C1=CC=C(O)C=C1O
Pimethixene maleate nic Acid PF-03084014 binds to GSPimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5 HT2A, 5 HT2B, 5 HT2C, 5 HT1A, 5 HT1B, 5 HT6, 5 HT7, Adrenergic 1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4. 4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.