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PubMed PMID: 30755068
PFI-3 was used at 1-10 µM final concentration in various in vitro assays
CAS Number: 86780-90-7
Kanazawa H
28)22-31-20(32-35-22)17-7-4-8-18(13-17)21(33)29-15-24(9-11-34-12-10-24)23-30-19(14-36-23)16-5-2-1-3-6-16/h1-8
SNDX-5613 - CAS# 2169919-21-3 midone PubMed PMID: 30755068SNDX 5613 is a potent and selective inhibitor of menin MLL binding with a Ki of 0. 15 nM. SNDX 5613 shows anti proliferative activity against multiple cell lines harboring MLLr translocations (MV4; 11, RS4; 11, MOLM 13, KOPN 8) with IC50 values ranging from 10 20 nM. Product information CAS Number: 2169919 21 3 Molecular Weight: 630. 82 Formula: C32H47FN6O4S Chemical Name: N ethyl 2 [4 [7 [[4 (ethylsulfonylamino)cyclohexyl]methyl] 2, 7 diazaspiro[3.
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