GNF-2 - CAS# 778270-11-4 60153 334949-59-6

334949-59-6

is a novel dual PI3K/mTOR inhibitor with an IC50 ~1 nM

1257044-40-8

NSC697923 was administered by IP injection at 10 mg/kg once per day in SH-SY5Y and NGP xenografts

1422955-31-4

GNF-2 - CAS# 778270-11-4 60153 334949-59-6GNF 2, CAS No. 778270 11 4, is an allosteric inhibitor of Bcr abl tyrosine kinase activity (IC50 = 267 nM); inhibits proliferation and induces apoptosis in Bcr abl expressing cells. Selective for Bcr abl over a panel of serine, threonine and tyrosine kinases. Non ATP competitive. Product information CAS Number: 778270 11 4 Molecular Weight: 374. 32 Formula: C18H13F3N4O2 Chemical Name: 3 (6 {[4 (trifluoromethoxy)phenyl]amino}pyrimidin 4 yl)benzamide