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5-a]pyrimidine-3-carbonitrile
[Zanamivir
U87MG (brain)
GW501516 is shown to be the most potent and selective PPARα agonists known with an EC50 of 1
PI3K inhibitor GSK1059615 inhibits PI3K in the PI3K/AKT kinase signaling pathway
UPF-648 Sodium Salt 436 5-a]pyrimidine-3-carbonitrileUPF 648 is a potent kynurenine 3 monooxygenase (KMO) inhibitor; exhibits highly active at 1 uM (81 10% KMO inhibition); ineffective at blocking KAT activity. IC50 value: 1 uM(81 10 % inhibition) Target: KMO inhibitor in vitro: BFF 122 inhibited KAT activity almost completely at both 1 and 0. 1 mM. The effect was still remarkable at 0. 01 mM (70 1 % inhibition). Product information CAS Number: 1465017 87 1 Molecular Weight: 281. 07 Formula: