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The anxiolytic-like effect of AP521 appears to be dose-related
Smiles: CC(C)(C)C1=CC(CN[C@@H]2[C@H](C(C3C=CC=CC=3)C3C=CC=CC=3)N3CCC2CC3)=C(C=C1)OC
and good oral bioavailability
MAZ51 (8 mg/kg
InChi: InChI=1S/C23H27N3O4
7-Deaza-2'-deoxy-7-iodoadenosine K4/6-IN-2 The anxiolytic-like effect of AP5217 Deaza 2' deoxy 7 iodoadenosine is a modified oligonucleotide containing 7 Deazaadenine. Product information CAS Number: 166247 63 8 Molecular Weight: 376. 15 Formula: C11H13IN4O3 Chemical Name: (2R,3S,5R) 5 {4 amino 5 iodo 7H pyrrolo[2,3 d]pyrimidin 7 yl} 2 (hydroxymethyl)oxolan 3 ol Smiles: NC1=NC=NC2=C1C(I)=CN2[C@H]1C[C@H](O)[C@@H](CO)O1 InChiKey: LIIIRHQRQZIIRT XLPZGREQSA N InChi: InChI=1S C11H13IN4O3 c12 5 2 16(8 1 6(18)7(3 17)19 8)11