EX-527 - SIRT1 Inhibitor. CAS# 49843-98-3 60071 Smiles: CC1=NN(C)C2OC(N)=C(C#N)C(C1=2)C1C=CC(=CC=1)C(F)(F)F

Name: EX-527 - SIRT1 Inhibitor. CAS# 49843-98-3 60071 Smiles: CC1=NN(C)C2OC(N)=C(C#N)C(C1=2)C1C=CC(=CC=1)C(F)(F)F
Brand: www.kampevent.nl
SKU: 47112399890
Price: 42.00 USD
Availability: InStock
Rating: 4.7119 (24 reviews)

SKU: 47112399890

4.7

USD42.00 USD76.00

Pay in 4 interest-free payments of $10.50 Learn more

Shipping Estimate
USA

USA

CAN

Ships within 48 hours · Estimated delivery Jul 30 - Aug 4

Description

Smiles: CC1=NN(C)C2OC(N)=C(C#N)C(C1=2)C1C=CC(=CC=1)C(F)(F)F

Formula: C27H36N4O5S

pp 103–107

and exhibit in vivo integration

106(8):1386-94

EX-527 - SIRT1 Inhibitor. CAS# 49843-98-3 60071 Smiles: CC1=NN(C)C2OC(N)=C(C#N)C(C1=2)C1C=CC(=CC=1)C(F)(F)FEX 527, CAS No. 49843 98 3, is a highly potent and selective inhibitor of SIRT1 with an IC50 ~98 nM. It does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 ~20 100 M). EX 527 has been used to investigate the relationship between SIRT1 mediated deacetylation of p53, p53 activity, and cell survival following DNA damage, as well as many other biological processes involving SIRT1. Product information CAS Number:

Exchange/Return Notes