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CC-115 demonstrating inhibition through 10 hours
Down-regulates BRD4 and induces tumor regression in CRPC xenografts in mice
NU7026 synergistically sensitizes I83 cells to Chlorambucil (CLB) 3
prostanoid biosynthesis
possibly through increasing intracellular cyclic AMP content in inflammatory cells
NPS-2143 Hydrochloride 10036 CC-115 demonstrating inhibition through 10NPS 2143, also known as SB 262470 and SB 262470A, is a Calcium sensing receptor antagonist (calcilytic). NPS 2143 stimulates release of parathyroid hormone. Calcilytic drugs have been researched as potential treatments for osteoporosis, and as the first such compound developed, NPS 2143 is still widely used in research into the CaSR receptor as well as design of newer calcilytic agents. Product information CAS Number: 324523 20 8 Molecular Weight:
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