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113(42):11865-11870
In an in vivo pharmacokinetic study in rats
3 nM (Human PKCα)
66% and 57% respectively
ClH/c30-20-15-23(41-17-20)24-27(37-12-10-35(11-13-37)21-4-2-1-3-5-21)42-29(33-24)34-26(38)19-14-22(31)25(32-16-19)36-8-6-18(7-9-36)28(39)40
BMS-262084 Catalog No.:M16812-C 113(42):11865-11870BMS 262084 is a potent, selective and irreversible inhibitor of factor XIa, with an IC50 of 2. 8 nM against human factor XIa. BMS 262084 also inhibits human tryptase (IC50=5 nM). BMS 262084 exhibits antithrombotic effects. Product information CAS Number: 253174 92 4 Molecular Weight: 425. 48 Formula: C18H31N7O5 Chemical Name: (2S,3R) 1 [4 (tert butylcarbamoyl)piperazine 1 carbonyl] 3 {3 [(diaminomethylidene)amino]propyl} 4 oxoazetidine 2 carboxylic
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