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19(2):202-8
100 mg/mL(136
0028) in TRAMP mice
3 hours in dogs
Chemical Name: (S)-N-(1-((4-(N-(tert-butyl)sulfamoyl)phenyl)amino)-1-oxo-3-phenylpropan-2-yl)-4-fluorobenzamide
Fidarestat Catalog No.:M25658-C 19(2):202-8Fidarestat (SNK 860) is an inhibitor of aldose reductase, with IC50s of 26 nM, 33 M, and 1. 8 M for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. Product information CAS Number: 136087 85 9 Molecular Weight: 279. 22 Formula: C12H10FN3O4 Chemical Name: (2S,4S) 6 fluoro 2',5' dioxo 2,3 dihydrospiro[1 benzopyran 4,4' imidazolidine] 2 carboxamide Smiles: