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SID 26681509 (1-30 μM) blocks high-mobility group box 1 (HMGB1)-induced TNF-α production dose dependently without altering cell viability
Formula: C16H11ClF3N3O2S
Noscapine hydrochloride ((S
Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia
6-dihydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1
M2698 Size:Contact [email protected] for quotation SID 26681509 (1-30 μM) blocksM2698 (MSC2363318A) is an orally active, ATP competitive, selective p70S6K and Akt dual inhibitor with IC50s of 1 nM for p70S6K, Akt1 and Akt3. M2698 can cross the blood brain barrier and has anti cancer activity. Product information CAS Number: 1379545 95 5 Molecular Weight: 449. 86 Formula: C21H19ClF3N5O Chemical Name: 4 {[(1S) 2 (azetidin 1 yl) 1 [4 chloro 3 (trifluoromethyl)phenyl]ethyl]amino}quinazoline 8 carboxamide Smiles: