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Piceatannol - CAS# 10083-24-6 035TING-Inducer-1 Smiles: C[C@H](OC1=CC(=CN=C1N)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl

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Description

Smiles: C[C@H](OC1=CC(=CN=C1N)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl

1-14H3/t20-

Chemical Name: (3Z)-5-methoxy-3-({3-[(E)-2-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]ethenyl]-1H-indazol-6-yl}methylidene)-2

is a DNA polymerase inhibitor potentially for the treatment of HBV infection

CH4O3S/c1-19-11-24-5-7-28-20(2)12-26(45-28)9-10-40-17-33-36(51-40)37-38(50-33)39(52-40)35-29(49-37)8-6-25(47-35)13-22(42)14-27-31(16-30(46-24)21(19)3)48-32(34(27)44-4)15-23(43)18-41

Piceatannol - CAS# 10083-24-6 035TING-Inducer-1 Smiles: C[C@H](OC1=CC(=CN=C1N)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1ClPiceatannol is a selective inhibitor of protein tyrosine kinase Syk. It could inhibit ICa, L, Ito, IKr, Ca2+ transients and Na+ Ca2+ exchange except IK1. Shows multiple biological activities such as anti inflammatory, antiproliferative and immunomodulatory effects. In vitro: The treatment of human myeloid cells with piceatannol suppressed TNF induced DNA binding activity of NF B. The effect of piceatannol was not restricted to myeloid cells, as TNF

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