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K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions[J]
Smiles: COC1=CC(/C=C/C(=O)OCC2C=CC(=CC=2)O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=CC=C1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
CAS Number: 1056881-04-9
respectively) and in human
2357 nM (PDGFRa)
9-Hydroxycamptothecin DEVD-CMK K-Ras(G12C) inhibitors allosterically control GTP9 Hydroxycamptothecin (9 Hydroxycamptothecine) is a Camptothecin derivative with anticancer activities extracted from patent WO1999001456A1, compound 23c. Product information CAS Number: 67656 30 8 Molecular Weight: 364. 35 Formula: C20H16N2O5 Chemical Name: (19S) 19 ethyl 8,19 dihydroxy 17 oxa 3,13 diazapentacyclo[11. 8. 0. 0,. 0,. 0,]henicosa 1(21),2,4,6,8,10,15(20) heptaene 14,18 dione Smiles: CC[C@]1(O)C2C=C3C4=NC5=CC=CC(O)=C5C=C4CN3C(=O)C=2COC1=O
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