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5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
the serum exposure of the compound is also good
CC1C=C(C=C(C=1)OC1N=C(O[C@H](CC)C(O)=O)C(F)=CC=1F)C1C=C(CN)C=CC=1
Formula: C10H19Br2N3
Pharmacological inhibition of EZH2 activity may provide a promising treatment for EZH2 mutant lymphoma
TCS HDAC6 20b Size:Contact [email protected] for quotation 5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amineTCS HDAC6 20b is a potent and selective inhibitor of histone deacetylase 6 (HADC6) . Histone deacetylases (HADC) are a series of enzymes that remove acetyl groups from an N acetyl lysine amino acid on a histone and make the histones to wrap the DNA more tightly, which prevent transcription. Mutation of HADC6 is associated with Alzheimer's disease. In HCT116 cells, TCS HDAC6 20b increased tubulin acetylation in a dose dependent way without a
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