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PX-478 was dosed to mice bearing tumor via IP injection or oral gavage at 100-120 mg/kg once per day
AM-0902 is highly permeable (average Papp=44
InChiKey: UBAXRAHSPKWNCX-UHFFFAOYSA-N
RPR107393 inhibits rat liver microsomal squalene synthase with an IC50 value of 0
) significantly reduces tumor burden and increases overall survival in xenograft-murine model of human-MM
Colchicine-d3 ster-d9 PX-478 was dosed to miceProduct information CAS Number: 1217625 62 1 Molecular Weight: 402. 46 Formula: C22H25NO6 Chemical Name: N [(10S) 3,4,5,14 tetramethoxy 13 oxotricyclo[9. 5. 0. 0,]hexadeca 1(16),2,4,6,11,14 hexaen 10 yl](H)acetamide Smiles: [2H]C([2H])([2H])C(=O)N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C2=CC=C(OC)C(=O)C=C21 InChiKey: IAKHMKGGTNLKSZ AVSFSGARSA N InChi: InChI=1S C22H25NO6 c1 12(24)23 16 8 6 13 10 19(27 3)21(28 4)22(29 5)20(13)14 7 9 18(26 2)17(25)11 15(14)16
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