Eltanexor Z-isomer Catalog No.:M20592-C JNJ-55511118 had excellent pharmacokinetic properties

JNJ-55511118 had excellent pharmacokinetic properties and achieved high receptor occupancy following oral administration

human TFA is a fragment of the renin substrate angiotensinogen

Thalidomide is initially promoted as a sedative

AZD5438 showed significant antiproliferative activity in human tumor cell lines (IC(50) range

InChiKey: DYKHBFJZCIEBJE-UPRLRBBYSA-N

Eltanexor Z-isomer Catalog No.:M20592-C JNJ-55511118 had excellent pharmacokinetic propertiesEltanexor Z isomer (KPT 8602 Z isomer) is the less active isomer of KPT 8602. KPT 8602 is a potent CRM1 inhibitor. IC50In Vitro: Eltanexor Z isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM 50 M, < 100 nM, > 30 M, respectively. In Vivo: Product information CAS Number: 1642300 78 4 Molecular Weight: 428. 29 Formula: C17H10F6N6O Chemical Name: (2Z) 3 {3 [3,5 bis(trifluoromethyl)phenyl] 1H 1,2,4 triazol 1