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4-dichlorophenyl)-N-methyl-1
25-Dihydroxyvitamin D3 ((24S)-24
InChi: InChI=1S/C30H32F6N4O2/c1-28(2
Cinnabarinic acid (0-100 μM) reduces cAMP formation in a concentration-dependent manner with an excellent potency and efficacy
Formula: C5H3N5O2S3
PF-CBP1 hydrochloride Size:2mg solid 4-dichlorophenyl)-N-methyl-1PF CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD). PF CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF CBP1 hydrochloride reduces LPS induced inflammatory cytokines expression (IL 1, IL 6 and IFN ) in primary macrophages. PF CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders,
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