FT011 Size:2mg solid InChi: InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8

InChi: InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8

75 nM and 18 nM in SupT1 cells

Chemical Name: Calcium 4-(((2S

C4H6O6/c1-24(2)39(56-46(62)64-5)44(60)58-23-48(15-16-48)21-38(58)42-52-22-37(55-42)28-9-13-32-31-12-8-26(18-33(31)49(50

AMD-3465 (2

FT011 Size:2mg solid InChi: InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8FT011 is an anti inflammatory and anti fibrotic agent that has been reported to attenuate organ damage in diabetic rats with cardiomyopathy and nephropathy. In diabetic rats, FT011 reduced retinal leukostasis, microglial density and mRNA levels of intercellular adhesion molecule 1 (ICAM 1). In Mller cells, FT011 reduced diabetes induced gliosis and vascular endothelial growth factor (VEGF) immunolabeling and the hyperglycaemic induced increase in ICAM