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5 μM with producing 50% inhibition
InChi: InChI=1S/C16H8ClF5N2O5/c17-8-5-10(19)9(18)4-7(8)13(25)24-15(28)23-11-2-1-6(14(26)27)3-12(11)29-16(20
ClH/c1-12(2
Solubility: DMSO 50 mg/mL (200
Chemical Name: 3-fluoro-5-(2-methyl-1
NPD-1335 Catalog No.:M26121-C 5 μM with producing 50%NPD1335 is a Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death. Product information CAS Number: 2376326 31 5 Molecular Weight: 455. 55 Formula: C28H29N3O3 Chemical Name: 3 {5 [(4aS,8aR) 4 oxo 3 (propan 2 yl)