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10 μM) extends neurites in the retinal ganglion cells (RGCs) compared with those in RGCs treated without Y-39983
Smiles: CC(C)C[C@H](NC(=O)[C@H]1O[C@@H]1C(O)=O)C(=O)NCCCCN=C(N)N
CAS Number: 125494-59-9
Discovery of GW870086: a potent anti-inflammatory steroid with a unique pharmacological profile
which performs important functions in regulation of the calcium balance and the bone metabolism
Dexpramipexole 60122 10 μM) extends neurites inDexpramipexole, also known as KNS 760704 and (R) Pramipexole, is under development for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrigs disease. The drug failed to show efficacy in terms of function or survival in a Phase III study of patients with ALS. Dexpramipexole is a low molecular weight, water soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics, and has been shown to be well