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Oclacitinib - CAS# 1208319-26-9 Catalog No.:M9848-2 rhIKK-1/rhIKK-2 heterodimer

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Description

rhIKK-1/rhIKK-2 heterodimer

CAS Number: 1414854-42-4

5-3(6)1-2-4(7)8/h2-3

CAS Number: 2446474-09-3

and marketed as Nimbex) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs

Oclacitinib - CAS# 1208319-26-9 Catalog No.:M9848-2 rhIKK-1/rhIKK-2 heterodimerOclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1 dependent cytokines involved in allergy and

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