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AGK2 - CAS# 304896-28-4 size:10mg solid The inhibition of mutant IDH2

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Description

The inhibition of mutant IDH2 and its neoactivity is therefore a potential therapeutic treatment for cancer

PubMed Central PMCID: PMC2362948

Daminozide

(2002) Blood

but has relatively minimal effects on general cell growth (>10 µM activity in the HFF assay)

AGK2 - CAS# 304896-28-4 size:10mg solid The inhibition of mutant IDH2AGK2, CAS No. 304896 28 4, is a potent and selective inhibitor of sirtuin 2 (SIRT2). Product information CAS Number: 304896 28 4 Molecular Weight: 434. 27 Formula: C23H13Cl2N3O2 Synonym: AGK 2 AGK 2 Chemical Name: 2 Cyano 3 [5 (2,5 dichlorophenyl) 2 furanyl] N 5 quinolinyl 2 propenamide Smiles: N#CC(=CC1=CC=C(O1)C1=CC(Cl)=CC=C1Cl)C(=O)NC1=CC=CC2=NC=CC=C21 InChiKey: SVENPFFEMUOOGK SDNWHVSQSA N InChi: InChI=1S C23H13Cl2N3O2 c24 15 6 8 19(25)18(12 15)22

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