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has a very favorable profile at efficacious doses in cynomolgus monkeys and mice
24 hours) strongly induces human A549 lung cancer cell apoptosis in a dose- and time-dependent manner
Smiles: COCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey: TZRXNWCLKYWDNH-UHFFFAOYSA-N
14 mg/mL (21
Eleclazine hydrochloride xacin meglumine has a very favorable profileEleclazine hydrochloride is a novel late Na+ current inhibitor with IC50 value of 0. 7 uM. target: Na+ current. IC50: 0. 7 uM. In vitro: Eleclazine hydrochloride inhibits ATX II enhanced late INa in ventricular myocytes, shorten the ATX II induced prolongation of APD, MAPD, QT interval, and decreased spatiotemporal dispersion of repolarization and ventricular arrhythmias. Inhibition by GS 6615 of ATX II enhanced late INa is strongly correlated with
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