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InChiKey: IHIUGIVXARLYHP-UXNJHFGPSA-N
PMID: 31927622
Atorvastatin is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease
Smiles: C[N+](C)(C)CC([O-])=O
Formula: C20H17Cl3N4
RAF265 enafil dihydrochloride InChiKey: IHIUGIVXARLYHP-UXNJHFGPSA-NCHIR 265 is an orally bioavailable small molecule with potential antineoplastic activity. CHIR 265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR 2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras Raf MEK ERK signaling pathway and are frequently