TAS-102 - CAS# 733030-01-8 Catalog No.:M6637-10S 1038/s41598-017-00212-w

1038/s41598-017-00212-w

CAS Number: 294623-49-7

MCT-16-0573

InChi: InChI=1S/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2

Chesler EJ

TAS-102 - CAS# 733030-01-8 Catalog No.:M6637-10S 1038/s41598-017-00212-wTAS 102, CAS No. 733030 01 8, is an investigational drug candidate for metastatic colorectal cancer. It contains trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a molar ratio of 1; 0. 5. Trifluridine is a nucleoside analog, and tipiracil hydrochloride is a thymidine phosphorylase inhibitor, which prevents rapid metabolism of trifluiridine, increasing the bioavailability of trifluiridine. After oral administration of TAS 102, TFT is