If any artifacts or enchantments were chosen as targets, and all of them are illegal targets as Pest Infestation tries to resolve, it won't resolve and none of its effects will happen
It is likely the most powerful red card in the format, but the context of the matchup is so important that its hard to justify play more than the pair

Grafted Butcher Greater Gargadon Grinding Station Hamlet Glutton Hellish Sideswipe Herald of Anguish High Fae Negotiator Ice Out Improvised Club Imskir Iron-Eater Incendiary Sabotage Ingenuity Engine Invasion of New Capenna Ironclad Revolutionary Jan Jansen, Chaos Crafter Johann's Stopgap Joo Dee, One of Many K'un-Lun Warrior Kellan's Lightblades Kingpin's Enforcers Krark-Clan Grunt Krark-Clan Ironworks Krark-Clan Ogre Krark-Clan Shaman Krark-Clan Stoker Krenko, Baron of Tin Street Kuldotha Flamefiend Kuldotha Rebirth Laurine, the Diversion Liberty Prime, Recharged Lithatog Lithobraking Lobelia, Defender of Bag End Magnetic Snuffler Makeshift Munitions Malevolent Noble Megatog Mica, Reader of Ruins Midgar, City of Mako Midgar, City of Mako Moonstone Eulogist Morbid Curiosity Nahiri's Sacrifice Oni-Cult Anvil Orcish Mechanics Orcish Vandal Osgir, the Reconstructor Oswald Fiddlebender Oxidda Daredevil Penregon Strongbull Phyrexia's Core Pia Nalaar Pia and Kiran Nalaar Piston Sledge Powerstone Fracture Priest of Yawgmoth Ravenous Intruder Ravenous Squirrel Realm-Scorcher Hellkite Reckless Detective Reckoner's Bargain Reshape Rowan's Grim Search Rust Elemental Rust Monster Rusted Slasher Sage of Lat-Nam Sarcatog Scrap Welder Scrapyard Recombiner Scrounge for Eternity Selfcraft Mechan

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which was before PSCT even existed