OSI-930 penem monohydrate 324(2):815-26

324(2):815-26

SP10 is a novel highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction

JNJ 63533054

[Epub ahead of print] PubMed PMID: 27941886

assesses after 6 days) inhibits TGF-β1-mediated proliferation of familial idiopathic pulmonary arterial hypertension (iPAH) pulmonary artery smooth muscle cells (PASMCs) at an IC50 of 295 nM

OSI-930 penem monohydrate 324(2):815-26OSI 930 is a selective thiophene derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI 930 inhibits stem cell factor receptor (c Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c Kit and VEGFR2 are overexpressed in a variety of cancers. Check for active clinical trials or closed