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C-178 Catalog No.:M17037-C Smiles: CC(CCC(=O)NCC(O)=O)C1CCC2C3C(CCC21C)C1(C)CCC(O)CC1CC3O

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Description

Smiles: CC(CCC(=O)NCC(O)=O)C1CCC2C3C(CCC21C)C1(C)CCC(O)CC1CC3O

2011 Dec 15

Dovitinib (50 and 75 mg/kg) results in 97% and 98% tumor growth inhibition

1 μM in both drug sensitive and multi-drug resistant cancer cell lines (i

LY364947 (2 μM) prevents TGF-β-induced epithelial−mesenchymal transition in NMuMg cells

C-178 Catalog No.:M17037-C Smiles: CC(CCC(=O)NCC(O)=O)C1CCC2C3C(CCC21C)C1(C)CCC(O)CC1CC3OC 178 is a potent and selective covalent inhibitor of STING. C 178 binds to Cys91 and suppresses the STING responses elicited by distinct bona fide activators in mouse but not human. Product information CAS Number: 329198 87 0 Molecular Weight: 322. 27 Formula: C17H10N2O5 Chemical Name: 5 nitro N {8 oxatricyclo[7. 4. 0. 0,]trideca 1(13),2,4,6,9,11 hexaen 5 yl}furan 2 carboxamide Smiles: [O ][N+](=O)C1=CC=C(O1)C(=O)NC1C=C2OC3=CC=CC=C3C2=CC=1 InChiKey:

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