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Lycorine - CAS# 476-28-8 2171 PubMed PMID: 15999992

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Description

PubMed PMID: 15999992

3-dihydro-2-benzofuran-5-carbonitrile

BMS-907351

The insulin sensitivity of the liver and peripheral tissues may be modulated indirectly by Rosiglitazone-mediated changes in levels of fatty acid or adipocyte-derived factors

GW-9662 has nanomolar IC50 versus PPARγ and is 10- and 600-fold less potent in binding experiments using PPARα and PPARδ

Lycorine - CAS# 476-28-8 2171 PubMed PMID: 15999992Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15. 24 nM. Lycorine downregulates the SCAP protein level without changing its transcription. Lycorine is also a melanoma vasculogenic inhibitor. Lycorine can be used for the study of prostate cancer and metabolic diseases. Product information CAS Number: 476 28 8 Molecular Weight: 287. 31 Formula: C16H17NO4

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