Pay in 4 interest-free payments of $22.50 Learn more
Ships within 48 hours · Estimated delivery Jul 31 - Aug 5
and irreversible inhibitor of cysteine proteases with IC50 values for inhibiting cathepsins K
21(4):271-281
It is specific for class I and class II HDACs
InChiKey: QNBLVYVBWDIWDM-BSLJOXIBSA-N
PPM1D is a potential therapeutic target in ovarian clear cell carcinomas
BEZ235 Tosylate 2357 (Givinostat) and irreversible inhibitor of cysteineDactolisib tosylate is also known as NVP BEZ 235 Tosylate. NVP BEZ235 is an imidazo[4,5 c]quinoline derivative that inhibits PI3K and mTOR kinase activity by binding to the ATP binding cleft of these enzymes. The IC50s for PI3K, , , are 4, 75, 7, 5 nM, respectively. It is also found to be as active against the mutant PI3KE545K or PI3KH1047R with IC50s of 5. 7 and 4. 6 nM, respectively. In human tumor cell lines, it is able to effectively and
US$ 26.99
US$ 28.00
US$ 34.00
US$ 12.00
US$ 12.75
US$ 25.00
US$ 10.00
US$ 28.00
US$ 26.00
US$ 34.00