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LW8 demonstrated strong anti-tumor efficacy in vivo and caused a decrease in HIF-1alpha expression in frozen-tissue immunohistochemical staining
4)5)11-14-46(8)28(44)10-9-23-24-19-42(2
InChi: InChI=1S/C39H50O20/c1-14(2)5-10-18-20(54-37-31(50)28(47)25(44)21(12-40)55-37)11-19(42)23-27(46)35(33(57-34(18)23)16-6-8-17(52-4)9-7-16)58-39-36(30(49)24(43)15(3)53-39)59-38-32(51)29(48)26(45)22(13-41)56-38/h5-9
100(11):6469-74
2 nM and 20
Mal-PEG1-acid il) LW8 demonstrated strong anti-tumor efficacyMal PEG1 acid is is a non cleavable 1 unit PEG ADC linker used in the synthesis of antibody drug conjugates (ADCs). Mal PEG1 acid is a PEG based PROTAC linker can be used in the synthesis of PROTACs. Product information CAS Number: 760952 64 5 Molecular Weight: 213. 19 Formula: C9H11NO5 Chemical Name: 3 [2 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)ethoxy]propanoic acid Smiles: OC(=O)CCOCCN1C(=O)C=CC1=O InChiKey: YTZFUAXOTCJZHP UHFFFAOYSA N InChi: InChI=1S
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