The mechanisms of otoprotection by Adenosine amine congener include inhibition of glutamate release via presynaptic A1 receptors and inhibition of voltage-gated Ca2+ channels
InChi: InChI=1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6
Cu/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25
Solubility: DMSO : 100 mg/mL (207
and PNU-101017 reduces the loss to 50%
Cucurbitacin E ole Acetate The mechanisms of otoprotection byCucurbitacin E is a natural compound which from the climbing stem of Cucumic melo L. Cucurbitacin E significantly suppresses the activity of the cyclin B1 CDC2 complex. Product information CAS Number: 18444 66 1 Molecular Weight: 556. 69 Formula: C32H44O8 Chemical Name: 6 {2,8 dihydroxy 3a,6,6,9b,11a pentamethyl 7,10 dioxo 1H,2H,3H,3aH,3bH,4H,6H,7H,9aH,9bH,10H,11H,11aH cyclopenta[a]phenanthren 1 yl} 6 hydroxy 2 methyl 5 oxohept 3 en 2 yl acetate