PG 01037 dihydrochloride Size:Contact [email protected] for quotation inducing apoptosis in several human

inducing apoptosis in several human solid tumor cell lines carrying tetracycline-regulated mutant p53 (IC50 = 10 µM in vitro)

SR9011 hydrochloride is a REV-ERBα/β agonist with IC50s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ

Smiles: C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC1C=CC(O)=CC=1)NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O

Jaeschke G

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

PG 01037 dihydrochloride Size:Contact [email protected] for quotation inducing apoptosis in several humanProduct information CAS Number: 675599 62 9 Molecular Weight: 554. 34 Formula: C26H28Cl4N4O Chemical Name: N [(2E) 4 [4 (2,3 dichlorophenyl)piperazin 1 yl]but 2 en 1 yl] 4 (pyridin 2 yl)benzamide dihydrochloride Smiles: Cl. Cl. O=C(NC C=C CN1CCN(CC1)C1=CC=CC(Cl)=C1Cl)C1C=CC(=CC=1)C1=CC=CC=N1 InChiKey: DACFFMAXBWGOKQ CZEFNJPISA N InChi: InChI=1S C26H26Cl2N4O. 2ClH c27 22 6 5 8 24(25(22)28)32 18 16 31(17 19 32)15 4 3 14 30 26(33)21 11 9 20(10 12 21)23 7