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SB216763 - CAS# 280744-09-4 60255 NLG919 abrogated IDO-induced suppression of

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Description

NLG919 abrogated IDO-induced suppression of antigen-specific T cells (OT-I or pmel- 1) in vitro

Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch

Jolkkonen J

Chemical Name: 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide

2009 Sep 21

SB216763 - CAS# 280744-09-4 60255 NLG919 abrogated IDO-induced suppression ofSB 216763, CAS No. 280744 09 4, is a glycogen synthase kinase 3 (GSK3) inhibitor, which can maintain mouse embryonic stem cells (mESCs) in a pluripotent state in the absence of exogenous leukemia inhibitory factor (LIF) when cultured on mouse embryonic fibroblasts (MEFs). SB 216763 is the first GSK3 inhibitor that can promote self renewal of mESC co cultured with MEFs for more than two months. Product information CAS Number: 280744 09 4 Molecular

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