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Dabrafenib Mesylate - CAS# 1195768-06-9 size:10mg solid Johnson-Levonas AO

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Description

Johnson-Levonas AO

eCollection 2014

and concomitantly increased level of sphingosine-1-phosphate (S1P) precursor ceramide in AML cells

TPR-MET cells by 44

it markedly augments the capacity of HGF at 1

Dabrafenib Mesylate - CAS# 1195768-06-9 size:10mg solid Johnson-Levonas AODabrafenib Mesylate, CAS No. 1195768 06 9, also known as GSK2118436 , is an orally bioavailable inhibitor of B raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B raf belongs to the the raf mil family of serine threonine protein kinases and plays a role in regulating the MAP kinase ERKs

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