PI3Kdelta inhibitor 1 ro-2-(4-methoxyphenyl)-4-oxo-1 5-benzothiazepin-5(2H)-yl]ethyl]methyl-d3-carbamic Acid 1-Chloroethyl Ester Chemical Name: 3-[(E)-2-(9-amino-7-ethoxyacridin-3-yl)diazen-1-yl]pyridine-2

Chemical Name: 3-[(E)-2-(9-amino-7-ethoxyacridin-3-yl)diazen-1-yl]pyridine-2

Smiles: OCCN(C(=O)CC1C=CC(=CC=1)C(=O)NO)C1C=CC=CC=1

BrH/c1-4-5-9-16-15(11-12-18(2)3)13-14-8-6-7-10-17(14)16

50-tetraisopropyl-32-methyl-17-(2-(methylthio)ethyl)-4

1 μM and for a shorter time also shows a drop in Lys9 methylation

PI3Kdelta inhibitor 1 ro-2-(4-methoxyphenyl)-4-oxo-1 5-benzothiazepin-5(2H)-yl]ethyl]methyl-d3-carbamic Acid 1-Chloroethyl Ester Chemical Name: 3-[(E)-2-(9-amino-7-ethoxyacridin-3-yl)diazen-1-yl]pyridine-2PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3K inhibitor with an IC50 of 1. 3 nM. Product information CAS Number: 2242109 74 4 Molecular Weight: 558. 69 Formula: C27H38N6O5S Chemical Name: N [2 methoxy 5 (1 methyl 4 {[(3R) 1 [2 (oxan 4 yl)ethyl]piperidin 3 yl]methoxy} 1H pyrazolo[3,4 b]pyridin 6 yl)pyridin 3 yl]methanesulfonamide Smiles: CN1N=CC2=C1N=C(C=C2OC[C@H]1CN(CCC1)CCC1CCOCC1)C1C=C(NS(C)(=O)=O)C(=NC=1)OC