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It inhibits KDM2A at IC50 ~1
9-dicarboxamide
InChi: InChI=1S/C38H50N6O5
resulting in hemorrhagic necrosis and a decrease in angiogenesis
Chemical Name: 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol
RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 It inhibits KDM2A at IC50RX 3117, also known as TV 1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX 3117 is taken up by cells through a carrier mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX DP) and triphosphate forms (RX TP). The triphosphate form is incorporated into
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