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CDK4/6-IN-2 indalone Perhexiline treatment increases the susceptibility

SKU: 83418331067

4.5
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Description

Perhexiline treatment increases the susceptibility of NB cells to antiblastic treatments

1-6H3/t12-

shows inhibitory activity

13-hexaene-2-carboxamide

InChi: InChI=1S/C21H31N5O2/c1-3-17(26-7-11-28-12-8-26)4-2-16(1)25-21-19-18(15-5-9-27-10-6-15)13-22-20(19)23-14-24-21/h13-17H

CDK4/6-IN-2 indalone Perhexiline treatment increases the susceptibilityCDK4 6 IN 2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2. 7 and 16 nM for CDK4 and CDK6, respectively. Product information CAS Number: 1800506 48 2 Molecular Weight: 506. 59 Formula: C27H32F2N8 Chemical Name: 5 [(4 ethylpiperazin 1 yl)methyl] N {5 fluoro 4 [4 fluoro 2 methyl 1 (propan 2 yl) 1H 1,3 benzodiazol 6 yl]pyridin 2 yl}pyrimidin 2 amine Smiles:

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