suggesting that GSK2239633A is a low to moderate clearance drug
S2101 is assumed to have approximately 50-fold stronger LSD1 inhibition activity than 2-PCPA in human cells
and this is reversed with cessation of ISCK03 treatment
8% in monkeys
with an EC50 of approximately 0
Withanolide A und Library suggesting that GSK2239633A is aWithanolide A, isolated from the indian herbal drug Ashwagandha (root of Withania somnifera), could regenerate neurites and reconstruct synapses in severely damaged neurons. Product information CAS Number: 32911 62 9 Molecular Weight: 470. 60 Formula: C28H38O6 Chemical Name: (1S,2S,4S,5R,10R,11S,14S,15S,18S) 15 [(1R) 1 [(2R) 4,5 dimethyl 6 oxo 3,6 dihydro 2H pyran 2 yl] 1 hydroxyethyl] 5 hydroxy 10,14 dimethyl 3 oxapentacyclo[9. 7. 0. 0,. 0,.