SAH-SOS1A dehydroandrographolide InChi: InChI=1S/C24H24FN3O3/c1-15-17(11-16-3-5-18(6-4-16)28-9-2-8-26-28)12-19-20(23(15)25)13-27(24(19)30)21-14-31-10-7-22(21)29/h2-6

InChi: InChI=1S/C24H24FN3O3/c1-15-17(11-16-3-5-18(6-4-16)28-9-2-8-26-28)12-19-20(23(15)25)13-27(24(19)30)21-14-31-10-7-22(21)29/h2-6

neo-Inositol

coli bacteria

CAS Number: 1373232-26-8

3R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-3-hydroxypropanamido]-4-carbamoylbutanoyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}acetamido)-3-carboxypropanamido]-3-carbamoylpropanamido]propanamido]-3-hydroxybutanoyl]pyrrolidin-2-yl]formamido}-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S

SAH-SOS1A dehydroandrographolide InChi: InChI=1S/C24H24FN3O3/c1-15-17(11-16-3-5-18(6-4-16)28-9-2-8-26-28)12-19-20(23(15)25)13-27(24(19)30)21-14-31-10-7-22(21)29/h2-6SAH SOS1A is a peptide based SOS1 KRAS protein interaction inhibitor. SAH SOS1A binds to wild type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106 175 nM), directly and independently blocks nucleotide association, impairs KRAS driven cancer cell viability, and exerts its effects by on mechanism blockade of the ERK MAPK phosphosignaling cascade downstream of KRAS. Product information CAS Number: 1652561 87 9