Atuveciclib (BAY-1143572) magacestat (LY450139) CC1=CC(N)=C2C=CC=CC2=[N+]1CCCCCCCCCC[N+]1=C2C=CC=CC2=C(N)C=C1C

CC1=CC(N)=C2C=CC=CC2=[N+]1CCCCCCCCCC[N+]1=C2C=CC=CC2=C(N)C=C1C

Formula: C10H11N3O5S

10(12):1219-23

Solubility: DMSO : ≥ 50 mg/mL (243

CAS Number: 2271036-44-1

Atuveciclib (BAY-1143572) magacestat (LY450139) CC1=CC(N)=C2C=CC=CC2=[N+]1CCCCCCCCCC[N+]1=C2C=CC=CC2=C(N)C=C1CAtuveciclib (BAY 1143572) is potent and highly selective PTEFb CDK9 inhibitor with IC50 values of 13 nM for CDK9 CycT and the ratio of IC50 values for CDK2 CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3 and GSK3 respectively. Product information CAS Number: 1414943 88 6 Molecular Weight: 387. 43 Formula: C18H18FN5O2S Chemical Name: [(3 {[4 (4 fluoro 2 methoxyphenyl) 1,3,5 triazin 2