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6)17-18-47(23
ABT-107 exhibits good bioavailability in mouse (orally
which are categorized as anti-inflammatory and inflammatory mediators
H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7
Knutson SK
RMC-5552 - CAS# 2382768-62-7 lufanide 6)17-18-47(23RMC 5552 is a potent and selective mTORC1 inhibitor. RMC 5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0. 14 nM and 0. 48 nM, respectively. RMC 5552 shows much lower pAKT inhibition (IC50 of 19 nM), resulting in mTORC1 mTORC2 selectivity approaching 40 fold. RMC 5552 has anti cancer activity. Product information CAS Number: 2382768 62 7 Molecular Weight: 1778. 13 Formula: C93H136N10O24 Chemical Name: (1R,2R,4S) 2 methoxy 4