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K02288 specifically inhibited the BMP-induced Smad pathway without affecting TGF-β signaling and induced dorsalization of zebrafish embryos
Stephens DM
2020 Aug 19
2017 May 11
15(5): 1083-1090
5Z-7-Oxozeaenol 12385 K02288 specifically inhibited the BMP-induced5Z 7 Oxozeaenol is a natural anti protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF R2, with IC50s of 8 nM and 52 nM, respectively. Product information CAS Number: 253863 19 3 Molecular Weight: 362. 37 Formula: C19H22O7 Synonym: FR148083 L783279 LL Z 1640 2 Chemical Name: (3S, 8S, 9S) 8, 9, 16 trihydroxy 14 methoxy 3 methyl 3, 4, 7, 8, 9, 10 hexahydro 1H 2 benzoxacyclotetradecine 1, 7 dione