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D-erythro-MAPP - CAS# 143492-38-0 16435 4-dimethoxyphenyl)methylidene]-5-[(1H-indol-3-yl)methylidene]-1-methylpiperidin-4-one

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Description

4-dimethoxyphenyl)methylidene]-5-[(1H-indol-3-yl)methylidene]-1-methylpiperidin-4-one

RO1138452 and RO3244794: characterization of structurally distinct

Significant efficacy can be achieved with GS-9876 doses that produces trough pSYK inhibition of <50%

CAS Number: 57647-79-7

Smiles: COC1=CC2[C@H]3CC[C@]4(C)C=CC[C@H]4[C@@H]3CCC=2C=C1C(N)=O

D-erythro-MAPP - CAS# 143492-38-0 16435 4-dimethoxyphenyl)methylidene]-5-[(1H-indol-3-yl)methylidene]-1-methylpiperidin-4-oneD erythro MAPP (D e MAPP) is a ceramidase inhibitor, with an IC50 of 1 5 M in vitro. Product information CAS Number: 143492 38 0 Molecular Weight: 361. 56 Formula: C23H39NO2 Chemical Name: N [(1S, 2R) 1 hydroxy 1 phenylpropan 2 yl]tetradecanamide Smiles: C[C@@H](NC(=O)CCCCCCCCCCCCC)[C@@H](O)C1C=CC=CC=1 InChiKey: YLAZEWZHIRBZDA NFBKMPQASA N InChi: InChI=1S C23H39NO2 c1 3 4 5 6 7 8 9 10 11 12 16 19 22(25)24 20(2)23(26)21 17 14 13 15 18 21 h13 15,17

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